Karsinoma sel basal (KSB) merupakan karsinoma kulit nonmelanoma (KKNM) menyerang terutama ras Kaukasian, jarang ditemukan di Asia, demikian pula di Indonesia. Sampai saat ini belum ada data lengkap bagaimana profil KSB di Palembang.
      Penelitian dilakukan secara deskriptif, data diambil dari rekam medis pasien KSB primer yang berobat atau di rujuk ke poliklinik rawat jalan IKKK- RSUP M Hoesin sejak Januari 2005 – Desember 2007. Hasil biopsi di konfirmasi di Bagian Patologi FK - RSUP M Hoesin Palembang. Dilakukan analisis chi-square berdasarkan jenis kelamin, usia, ukuran lesi, lokasi, tipe KSB berdasarkan gambaran klinis dan histopatologis (p<0,05)
      Pada penelitian ini didapatkan 48 kasus KSB primer (0,30%) dari 15845 kunjungan pasien baru, terdiri atas laki-laki 18 (35,4%) dan perempuan 30 (64,6%). Perbandingan laki-laki dan perempuan adalah 1: 1,8; usia pasien antara 32-88 tahun, laki-laki usia termuda 35 tahun, tertua 75 tahun, perempuan usia termuda 32 tahun, tertua 88 tahun. Lokasi lesi terbanyak di regio (R) bukalis sebanyak 20 (35,4%), diikuti berturut-turut R ala nasi 10 (20,8%), hidung ( pangkal dan puncak hidung) dan R palpebre masing-masing sebanyak 6 (12,5%), di R parietal 5 (10,4%) dan R frontalis 1(2,2%). Gambaran klinis terbanyak tipe nodular sebanyak 32 (67,5%) diikuti tipe pigmented 16 (33,3%) dan ukuran lesi terbanyak T1 42 ((87,5%) diikuti T2 6 (12,5%). Gambaran histopatologis terbanyak tipe nodular 32 (66,6%) diikuti berturut-turut tipe pigmented 13 (27%), tipe metatipikal 2 (4,2%), dan tipe infiltratif 1(2,2%).
    Kesimpulan penelitian ini ialah tidak terdapat perbedaan secara`signifikan KSB pada laki-laki dan perempuan; distribusi lesi terbanyak di regio bukalis; ukuran lesi terbanyak T1 diikuti T2; gambaran klinis terbanyak tipe nodular diikuti tipe pigmented. Perlu penelitian lebih lanjut untuk melihat profil KSB di Indonesia (MDVI 2011; 38/2:78-83)

Kata kunci : Karakteristik karsinoma sel basal, analisis epidemiologi

       Basal cell carcinoma (BCC) is a predominant non melanoma skin cancer (NMSC) in Caucacia populations, Asia is uncommon, in Indonesia BCC is not frequently seen. The profile BCC in Palembang have not been analyzed before.
      A discriptive study of BCC profile using the medical records of 48 cases primary BCC was eligible in outpatient clinic General Hospital M Hoesin Palembang since January 2005 – December 2007. chi-square analyzed the gender, age distribution, site and size of the lesions, clinical appearance and histopathologic features (p<0,05).
      In this study we found total primary BCC was 48(0,30%) among 15845 new outpatients. male:female ratio was 1:1,8, the youngest age of male patients was 35 years, oldest 75 years, the youngest age of female patients was 32 years, oldest 88 years; the size of the lesions was T1 42 (87,5%) and T2 6 (12,5%). The site of predilection was mostly noticed on the cheeks 20 (35,4%), respectively followed ala nasi 10 (20,8%), nose and lower eyelid 6 (12,5%). The clinical appearance showed predominantly nodular type 32 (67,5%), respectively followed.pigmented type 16 (33,3%). The histopathological pattern showed nodular type 32 (66,6%), pigmented type 13 (27%), metatypical type 2 (4,2%), and infiltrative type 1 (2,2%)
      There was no significant different male : female ratio (1:1,8); distribution of lesions was most common on the cheeks. Size of the lesions was mostly T1 followed by T2, clinical appearance was nodular type followed pigmented type; however we need to study further about the characteristics of BCC in Indonesia.(MDVI 2011; 38/2:78-83)

Keywords: characteristics basal cell carcinoma, epidemiology analysis