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Dermatitis atopik (DA) adalah penyakit kulit inflamasi kronik dengan karakteristik terdapatnya pruritus yang bersifat kronik residif; memiliki distribusi serta morfologi lesi sesuai dengan usia; disertai riwayat atopi pada diri sendiri atau keluarga. Pada DA sering terdapat peningkatan imunoglobulin E (Ig E) total dan spesifik. Konsep alergi pada DA masih kontroversi karena eksaserbasi lesi kulit pada penderita DA dapat dicetuskan akibat kontak atau inhalasi aeroalergen yaitu tungau debu rumah, polen, bulu binatang atau akibat makanan yang mengandung  alergan, dan DA dapat membaik dengan strategi pencegahan paparan bahan alergan hirup dan makanan. Atopy patch test (APT) adalah tes tempel dengan mengaplikasikan alergan secara epikutaneus untuk menginduksi sensitisasi yang dimediasi oleh Ig E sehingga menimbulkan reaksi eksema. APT dapat digunakan sebagai alat bantu diagnostik untuk DA yang dicetuskan oleh alergen hirup dan alergen makanan, akan tetapi pemeriksaan ini masih memerlukan standardisasi teknik pemeriksaan.  Pada makalah ini dibahas indikasi, pemilihan bahan alergen, tehnik pelaksanaan, reprodusibilitas, sensitivitas dan spesifisitas serta manfaat APT untuk DA.

Kata kunci: atopy patch test, dermatitis atopik, diagnosis

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Atopic dermatitis (AD) is a chronic inflammatory skin disease. AD is characterized by reccurent intense pruritus; a typically age-related distribution and skin morfology; patient or family history of atopy. Atopic sensitization with increased total and specific immunoglobulin E (Ig E) level is a common finding in patients suffering from AD. The role of allergy in AD is still controversial, some patients with AD suffer from exaserbation of skin lesion after contact with or inhalation of aeroallergen such as house dust mite, pollen, animal dander or after ingestion of allergy-inducing foods and improved after appropriate avoidance strategies. Atopy patch test (APT), a useful diagnostic method in diagnosing AD; specially for airborne or dietary allergen—induced AD, is a epicutaneous patch test with allergen known to induce an Ig E- mediatred sensitizationand the evaluation of an occuring eczematous skin reaction. Indications for Atopy patch testing, allergens used (aeroallergens and foods), test material and technique, reproducibility, sensitivity and specificity, including APT benefits are reviewed on the basis of available literatures.

Kata kunci: atopy patch test, atopic dermatitis, diagnosis