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Lesi pustular merupakan satu dari gambaran klinis yang dapat dijumpai pada berbagai penyakit kulit pada neonatus. Beberapa tidak berbahaya dan dapat sembuh sendiri, namun ada yang mengancam jiwa sehingga diagnosis yang cepat dan tepat sangat perlu dilakukan. Manifestasi klinis, pemeriksaan penunjang, diagnosis banding, terapi, dan prognosis dermatosis pustular pada neonatus dijelaskan secara sistematik.

Dermatosis pustular pada neonatus agak sering ditemukan, namun diagnosis bandingnya sangat banyak. Berbagai penyakit tersebut, antara lain infeksi bakterial, herpes simpleks neonatorum (HSN), varisela, kandidosis, skabies, sifilis kongenital, eritema toksikum neonatorum (ETN), transient neonatal pustular melanosis (TNPM), miliaria, akropustulosis infantil, akne neonatorum dan neonatal cephalic pustulosis, dapat dibedakan dengan mengidentifikasi isi pustul dengan pewarnaan Wright, giemsa, Tzank, gram, sediaan KOH, dan kultur pus. Apabila hasilnya negatif, maka kemungkinan etiologi non-infeksiosa dapat dipertimbangkan.

Diagnosis yang tepat dan cepat perlu dilakukan karena beberapa penyakit pada neonatus dengan lesi pustular dapat menyebabkan kematian.

Kata kunci : dermatosis pustular, neonatus, infeksiosa, noninfeksiosa

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Pustules are one of clinical manifestation of neonatus skin diseases. These clinical findings can be trully life threatening but in contrast, several of the conditions  are self-limited. Accurate and prompt diagnosis are  essential. Clinical manifestations, laboratory findings, differential diagnosis, treatment, and prognosis of pustular dermatoses are explained below.

Pustular dermatosis are common in the newborn period,  it is frequently difficult to diagnose because many diseases also accompanied by pustules. The examples are bacterial infections, herpes simplex neonatorum (HSN), varicella, candidosis, scabies, congenital syphilis, erythema toxicum neonatorum (ETN),  transient neonatal pustular melanosis (TNPM), miliaria, infantil acropustulosis, acne neonatorum and neonatal cephalic pustulosis. These diseases can be distinguished by examining the contents of the pustules using wright, giemsa, Tzank, gram stain, KOH examination, and culture of the pustules. If negative, non-infectious etiology must be considered.

            Accurate and prompt diagnosis is essential because these neonate disease can be trully life threatening.

Key words : pustular dermatosis, neonatus, infectiosa, noninfectiosa